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Article

Functional genomics approaches to neurodegenerative diseases.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Sept 2008

Rubinsztein David C

Abstract excerpt

Many of the neurodegenerative diseases that afflict humans are characterised by the protein aggregation in neurons. These include complex diseases like Alzheimer's disease and Parkinson's disease, and Mendelian diseases caused by polyglutamine expansion mutations [like Huntington's disease (HD) and various spinocerebellar ataxias (SCAs), like SCA3]. A range of functional genomic strategies have been used to try...

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PMID: 18665420
DOI: 10.1007/s00335-008-9130-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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