Article
Estimating the rate of gene conversion on human chromosome 21.
American journal of human genetics - 1 Sept 2004
Padhukasahasram Badri, Marjoram Paul, Nordborg Magnus
Abstract excerpt
There is a growing recognition that gene conversion can be an important factor in shaping fine-scale patterns of linkage disequilibrium in the human genome. We devised simple multilocus summary statistics for estimating gene-conversion rates from genomewide polymorphism data sets. In addition to being computationally feasible for very large data sets, these summaries were designed to yield robust estimates of...
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