Article
The molecular genetics of Alzheimer's disease.
Molecular neurobiology - 1 Jan 2000
Mullan M, Crawford F
Abstract excerpt
The major pathological characteristic of Alzheimer's disease (AD) is the abnormal deposition of beta-amyloid peptide (A beta) in the brain. In some early onset cases, the disease develops because of mutations in the gene coding for beta-amyloid precursor protein (beta APP). However, the majority...
Topics
- Age of Onset
- Alzheimer Disease
- Amyloid beta-Protein Precursor
- Chromosomes, Human, Pair 14
- Chromosomes, Human, Pair 19
- Humans
- Mutation