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Article

Conserved amino acid sequences confer nuclear localization upon the Prophet of Pit-1 pituitary transcription factor protein.

Gene - 21 Jul 2004

Guy J Chico, Hunter Chad S, Showalter Aaron D, Smith Timothy P L, Charoonpatrapong Kanokwan, Sloop Kyle W, Bidwell Joseph P, Rhodes Simon J

Abstract excerpt

Prophet of Pit-1 (PROP1) is a homeodomain transcription factor essential for development of the mammalian anterior pituitary gland. Studies of human patients and animal models with mutations in their Prop1 genes have established that PROP1 is required for the correct development or sustained function of the hormone-secreting cells that regulate physiological pathways controlling growth, reproduction, metabolism,...

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Source

Identifiers

PMID: 15246537
DOI: 10.1016/j.gene.2004.04.022

Genes

PROP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Conserved amino acid sequences confer nuclear localization upon the Prophet of Pit-1 pituitary transcription factor protein.PMID 15246537Read ↗

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