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Article

A comprehensive evaluation of IL4 variants in ethnically diverse populations: association of total serum IgE levels and asthma in white subjects.

The Journal of allergy and clinical immunology - 1 Jul 2004

Basehore Monica J, Howard Timothy D, Lange Leslie A, Moore Wendy C, Hawkins Gregory A, Marshik Patricia L, Harkins Michelle S, Meyers Deborah A, Bleecker Eugene R

Abstract excerpt

BACKGROUND: The role of variation in the IL4 gene in asthma and allergy susceptibility is controversial. This cytokine is important in IgE isotype switching and the regulation of allergic inflammation; however, published studies have not delineated the specific role of variation in this gene in allergic disorders. OBJECTIVE: We sought to identify single nucleotide polymorphisms (SNPs) in IL4 and to evaluate the...

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Source

Identifiers

PMID: 15241348
DOI: 10.1016/j.jaci.2004.05.035

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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