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Article

Eotaxin polymorphisms and serum total IgE levels in children with asthma.

The Journal of allergy and clinical immunology - 1 Feb 2006

Raby Benjamin A, Van Steen Kristel, Lazarus Ross, Celedón Juan C, Silverman Edwin K, Weiss Scott T

Abstract excerpt

BACKGROUND: Eotaxin (chemokine, CC motif, ligand; CCL11) is a potent eosinophil chemoattractant strongly implicated in the pathobiology of asthma. Genetic variation at the CCL11 locus has been correlated with serum total IgE, blood eosinophil counts, and circulating eotaxin protein levels in several case-control asthma studies. Family-based association studies of CCL11 genetic variants have not been reported to...

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Source

Identifiers

PMID: 16461130
DOI: 10.1016/j.jaci.2005.10.041

Genes

CCL11
FEV

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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