Article
Relationship between polymorphisms in IL4 and asthma in Japanese women: the Kyushu Okinawa Maternal and Child Health Study.
Journal of investigational allergology & clinical immunology - 1 Jan 2013
Miyake Y, Tanaka K, Arakawa M
Abstract excerpt
BACKGROUND: Interleukin (IL) 4 plays a critical role in immune responses by acting as a growth factor for type 2 helper T cells and inducing immunoglobulin (Ig) class switching to IgE. Epidemiological evidence of the relationship between single-nucleotide polymorphisms (SNPs) in IL4 and asthma is inconsistent. OBJECTIVES: We examined the association between the IL4 SNPs rs2243250, rs2070874, rs2227284, and...
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