Article
Maternal and environmental factors in early cloned embryo development.
Cytogenetic and genome research - 1 Jan 2004
Gao S, Latham K E
Abstract excerpt
Cloning by somatic cell nuclear transfer (SCNT) in mammals has revealed the remarkable ability of an oocyte to reprogram somatic cell nuclei and induce them to recapitulate the developmental program. Despite the success, cloning remains very inefficient. This review summarizes recent observations from cloning in mice that reveal some of the likely causes for the present inefficiency. One cause appears to be the...
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