Article
Incidence of apoptosis, cell proliferation and P53 expression in renal cell carcinomas.
Anticancer research - 1 Jan 2000
Tannapfel A, Hahn H A, Katalinic A, Fietkau R J, Kühn R, Wittekind C W
Abstract excerpt
BACKGROUND: Given the growing evidence that proliferation indices may be of prognostic significance in renal cell carcinoma and that parameters of cell loss (usually, but not exclusively due to programmed cell death) are biologically relevant, identification and quantitation of apoptosis and possible regulatory factors are of considerable clinical importance. MATERIALS AND METHODS: Apoptotic cells were identified...
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