Anti-apoptosis gene, survivin, and prognosis of neuroblastoma

Abstract excerpt

Neuroblastoma may be aggressive with a dismal outcome or regress spontaneously. Prognostic factors including age, stage, and ploidy, N-myc amplification, and histology are necessary to direct treatment. Gene products controlling apoptosis may modulate neuroblastoma's variable course. 1 Pritchard J Hickman JA Why does stage 4s neuroblastoma regress spontaneously?. Lancet. 1994; 344: 869-870 Abstract PubMed Scopus...

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