Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Apoptotic Signaling Pathways in Glioblastoma and Therapeutic Implications

1 Jan 2017

Abstract excerpt

Glioblastoma multiforme (GBM) is the most hostile type of brain cancer. Its aggressiveness is due to increased invasion, migration, proliferation, angiogenesis, and a decreased apoptosis. In this review, we discuss the role of key regulators of apoptosis in GBM and glioblastoma stem cells. Given their importance in the etiology and pathogenesis of GBM, these signaling molecules may represent potential therapeutic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Mechanisms and Therapy
Share to Cell death mechanisms and regulation
Share to MicroRNA in disease regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29259986
DOI: 10.1155/2017/7403747

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Apoptotic Signaling Pathways in Glioblastoma and Therapeutic ImplicationsPMID 29259986Read ↗

Glioblastoma Tumor Initiating Cells: Therapeutic Strategies Targeting Apoptosis and MicroRNA PathwaysSemantic proximity Read ↗

Deregulated Signaling Pathways in Glioblastoma Multiforme: Molecular Mechanisms and Therapeutic TargetsSemantic proximity Read ↗

Survival signalling and apoptosis resistance in glioblastomas: opportunities for targeted therapeuticsSemantic proximity Read ↗

Mechanisms of Cell Cycle Arrest and Apoptosis in GlioblastomaSemantic proximity Read ↗

Signaling pathways and therapeutic approaches in glioblastoma multiforme (Review)Semantic proximity Read ↗

Glioblastoma multiforme: insights into pathogenesis, key signaling pathways, and therapeutic strategiesSemantic proximity Read ↗

Identification of survival‐related genes of the phosphatidylinositol 3′‐kinase signaling pathway in glioblastoma multiformeSemantic proximity Read ↗

How to train glioma cells to die: molecular challenges in cell deathSemantic proximity Read ↗

Glioblastoma Multiforme Oncogenomics and Signaling PathwaysSemantic proximity Read ↗

Genetic and signaling pathway alterations in glioblastoma: relevance to novel targeted therapies.Semantic proximity Read ↗

Beyond effector caspase inhibitionSemantic proximity Read ↗

CD95 maintains stem cell-like and non-classical EMT programs in primary human glioblastoma cellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.