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Article

Whole-genome single nucleotide polymorphism-based linkage analysis in spondyloarthritis multiplex families reveals a new susceptibility locus in 13q13.

Annals of the rheumatic diseases - 1 Jul 2016

Costantino Félicie, Chaplais Emmanuel, Leturcq Tifenn, Said-Nahal Roula, Leboime Ariane, Zinovieva Elena, Zelenika Diana, Gut Ivo, Charon Céline, Chiocchia Gilles, Breban Maxime, Garchon Henri-Jean

Abstract excerpt

OBJECTIVE: Spondyloarthritis (SpA) is a chronic inflammatory disorder with high heritability but with complex genetics. Apart from HLA-B27, most of the underlying genetic components remain to be identified. We conducted a whole-genome high-density non-parametric linkage analysis to identify new genetic factors of susceptibility to SpA. METHODS: 914 subjects including 462 with SpA from 143 multiplex families were...

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Share to Chromosomes, Human, Pair 13
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26275432
DOI: 10.1136/annrheumdis-2015-207720

Genes

FREM2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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