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Article

The septic shock associated HSPA1B1267 polymorphism influences production of HSPA1A and HSPA1B.

Intensive care medicine - 1 Sept 2004

Temple Suzanna E L, Cheong Karey Y, Ardlie Kristin G, Sayer David, Waterer Grant W

Abstract excerpt

OBJECTIVE: To identify a functional polymorphic site(s) within HSPA1A and/or HSPA1B which is in linkage disequilibrium with the silent mutation HSPA1B1267A>G and explains its association with septic shock. SUBJECTS: The promoter region of HSPA1A and HSPA1B was sequenced in 100 healthy whites. Stimulation experiments were performed on 36 healthy subjects. MEASUREMENTS AND RESULTS: Sequencing the HSPA1A and HSPA1B...

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Share to Gene Frequency
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymerase Chain Reaction

Share to Polymorphism, Genetic

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Source

Identifiers

PMID: 15232679
DOI: 10.1007/s00134-004-2359-5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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