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Diagnostic and Prognostic Risk Assessment of Heat Shock Protein HSPA1B rs2763979 Gene Variant in Asthma.

Genes - 16 Dec 2022

Faisal Salwa, Abdelaal Sherouk, Jeraiby Mohammed A, Toaimah Fatihi Hassan Soliman, Kattan Shahad W, Abdel-Gawad Abdelhady Ragab, Riad Eman, Toraih Eman A, Fawzy Manal S, Ibrahim Ahmed

Abstract excerpt

Given the significant role the heat shock protein Hsp70 plays in modulating cellular homeostasis in several chronic inflammatory disorders, the genetic variation of the inducible HSP70 (HSPA1B) gene may impact protein expression and disease phenotype. The HSPA1B rs2763979 variant has been associated with multiple inflammatory scenarios, but no previous studies have explored its association with asthma. In this...

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Identifiers

PMID: 36553658
DOI: 10.3390/genes13122391
PMCID: PMC9778050

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Source receipt: pubmed, retrieved 7 Sept 2026.

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