Article
Over-expression of Rififylin, a new RING finger and FYVE-like domain-containing protein, inhibits recycling from the endocytic recycling compartment.
Molecular biology of the cell - 1 Oct 2004
Coumailleau Franck, Das Vincent, Alcover Andres, Raposo Graça, Vandormael-Pournin Sandrine, Le Bras Stéphanie, Baldacci Patricia, Dautry-Varsat Alice, Babinet Charles, Cohen-Tannoudji Michel
Abstract excerpt
Endocytosed membrane components are recycled to the cell surface either directly from early/sorting endosomes or after going through the endocytic recycling compartment (ERC). Studying recycling mechanisms is difficult, in part due to the fact that specific tools to inhibit this process are scarce. In this study, we have characterized a novel widely expressed protein, named Rififylin (Rffl) for RING Finger and...
Topics
- Amino Acid Sequence
- Animals
- Apoptosis Regulatory Proteins
- Base Sequence
- Endocytosis
- Endosomes
- HeLa Cells
- Humans
- Intracellular Membranes
- Mice