Article
The annexin 2/S100A10 complex controls the distribution of transferrin receptor-containing recycling endosomes.
Molecular biology of the cell - 1 Dec 2003
Zobiack Nicole, Rescher Ursula, Ludwig Carsten, Zeuschner Dagmar, Gerke Volker
Abstract excerpt
The Ca2+- and lipid-binding protein annexin 2, which resides in a tight heterotetrameric complex with the S100 protein S100A10 (p11), has been implicated in the structural organization and dynamics of endosomal membranes. To elucidate the function of annexin 2 and S100A10 in endosome organization and trafficking, we used RNA-mediated interference to specifically suppress annexin 2 and S100A10 expression....
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