Article
Recycling of Raft-associated prohormone sorting receptor carboxypeptidase E requires interaction with ARF6.
Molecular biology of the cell - 1 Nov 2003
Arnaoutova Irina, Jackson Catherine L, Al-Awar Omayma S, Donaldson Julie G, Loh Y Peng
Abstract excerpt
Little is known about the molecular mechanism of recycling of intracellular receptors and lipid raft-associated proteins. Here, we have investigated the recycling pathway and internalization mechanism of a transmembrane, lipid raft-associated intracellular prohormone sorting receptor, carboxypeptidase E (CPE). CPE is found in the trans-Golgi network (TGN) and secretory granules of (neuro)endocrine cells. An...
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