Article
Rab coupling protein (RCP), a novel Rab4 and Rab11 effector protein.
The Journal of biological chemistry - 5 Apr 2002
Lindsay Andrew J, Hendrick Alan G, Cantalupo Giuseppina, Senic-Matuglia Francesca, Goud Bruno, Bucci Cecilia, McCaffrey Mary W
Abstract excerpt
Rab4 and Rab11 are small GTPases belonging to the Ras superfamily. They both function as regulators along the receptor recycling pathway. We have identified a novel 80-kDa protein that interacts specifically with the GTP-bound conformation of Rab4, and subsequent work has shown that it also interacts strongly with Rab11. We name this protein Rab coupling protein (RCP). RCP is predominantly membrane-bound and is...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.