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Article

TATA-binding protein mutants that are lethal in the absence of the Nhp6 high-mobility-group protein.

Molecular and cellular biology - 1 Jul 2004

Eriksson Peter, Biswas Debabrata, Yu Yaxin, Stewart James M, Stillman David J

Abstract excerpt

The Saccharomyces cerevisiae Nhp6 protein is related to the high-mobility-group B family of architectural DNA-binding proteins that bind DNA nonspecifically but bend DNA sharply. Nhp6 is involved in transcriptional activation by both RNA polymerase II (Pol II) and Pol III. Our previous genetic studies have implicated Nhp6 in facilitating TATA-binding protein (TBP) binding to some Pol II promoters in vivo, and we...

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Source

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Identifiers

PMID: 15226442
DOI: 10.1128/MCB.24.14.6419-6429.2004
PMCID: PMC434259

Genes

TBP
BRF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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