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Article

Chromatin-mediated transcriptional regulation by the yeast architectural factors NHP6A and NHP6B.

The EMBO journal - 15 Dec 2000

Moreira J M, Holmberg S

Abstract excerpt

The Saccharomyces cerevisiae NHP6A and NHP6B proteins are chromatin architectural factors, functionally and structurally related to the mammalian high mobility group (HMG)-1 and -2 proteins, a family of non-sequence-specific DNA binding proteins. nhp6a nhp6b mutants have various morphological defects and are defective in the induced expression of several RNA polymerase II-transcribed genes. We found that NHP6A/B...

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Identifiers

PMID: 11118215
DOI: 10.1093/emboj/19.24.6804
PMCID: PMC305882

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