Article
Strain-dependent vascular remodeling: the "Glagov phenomenon" is genetically determined.
Circulation - 13 Jul 2004
Korshunov Vyacheslav A, Berk Bradford C
Abstract excerpt
BACKGROUND: Atherosclerosis of the carotid artery, called intima-media thickening (IMT), is a form of vascular remodeling that is an important predictor for cardiovascular events and has a strong genetic component. METHODS AND RESULTS: Recently, we established a mouse model of vascular remodeling based on partial ligation of the carotid, which is relevant to the "Glagov phenomenon." We hypothesized that there...
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