Article

Unraveling the Sex-Dependent Relationship Between Central, Peripheral and Cerebral Arteries Function in a Mouse Model of Marfan Syndrome: Benefits of Exercise Training on Vascular Function and Blood Flow

2025-05-16

Abstract excerpt

Marfan syndrome (MFS) is a connective tissue disorder caused by mutations in the fibrillin-1 gene, affecting multiple systems including the musculoskeletal, cardiovascular, and pulmonary systems. Vascular complications, particularly aortic root aneurysm, dissection, and rupture, are hallmark features of MFS. In recent decades, advances in diagnostics and treatments have significantly improved life expectancy for i...

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Literature Corpus work: f8249e40-e8c1-5253-81f8-cf138600cc63
DOI: 10.20944/preprints202505.1302.v1

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