Article
Genetic susceptibility of the arterial wall is an important determinant of atherosclerosis in C57BL/6 and FVB/N mouse strains.
Arteriosclerosis, thrombosis, and vascular biology - 1 Aug 2011
Shim Jeong, Handberg Aase, Ostergren Caroline, Falk Erling, Bentzon Jacob F
Abstract excerpt
OBJECTIVE: How genetic variations among inbred mouse strains translate into differences in atherosclerosis susceptibility is of significant interest for the development of new therapeutic strategies. The objective of the present study was to examine whether genetically controlled arterial wall properties influence atherosclerosis susceptibility in FVB/N (FVB) and C57BL/6 (B6) apolipoprotein E knockout (apoE(-/-))...
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