Article
Role of tumor necrosis factor-alpha (C-863A) polymorphism in pathogenesis of inflammatory bowel disease in Northern India.
Journal of gastrointestinal cancer - 1 Jun 2012
Ahirwar Dinesh K, Kesarwani Pravin, Singh Ranjana, Ghoshal Uday Chand, Mittal Rama Devi
Abstract excerpt
OBJECTIVE: Inflammatory bowel diseases (IBDs), namely ulcerative colitis (UC) and Crohn's disease (CD), are characterized by chronic and idiopathic inflammatory conditions of gastrointestinal tract that are immunologically mediated. Single nucleotide polymorphisms in cytokine genes have been reported to modulate inflammation. Therefore, we analyzed the association of pro/anti-inflammatory cytokine genes...
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