Article
Cytokine gene polymorphisms are associated with irritable bowel syndrome: a systematic review and meta-analysis.
Neurogastroenterology and motility - 1 Dec 2012
Bashashati M, Rezaei N, Bashashati H, Shafieyoun A, Daryani N E, Sharkey K A, Storr M
Abstract excerpt
BACKGROUND: Low-grade inflammation has been increasingly implicated in the pathophysiology of irritable bowel syndrome (IBS). Imbalances of pro- and anti-inflammatory cytokines and polymorphisms in cytokine genes have been reported in IBS; however, these findings have not been consistently observed. This may be due to small sample sizes and differences in ethnicities. Therefore, we performed a meta-analysis on...
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