Proinflammatory cytokine gene polymorphisms in irritable bowel syndrome.

doi:10.1007/s10875-009-9342-4

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Article

Proinflammatory cytokine gene polymorphisms in irritable bowel syndrome.

Journal of clinical immunology - 1 Jan 2010

Barkhordari Elham, Rezaei Nima, Ansaripour Bita, Larki Pegah, Alighardashi Maryam, Ahmadi-Ashtiani Hamid Reza, Mahmoudi Mahdi, Keramati Mohammad-Reza, Habibollahi Peiman, Bashashati Mohammad, Ebrahimi-Daryani Naser, Amirzargar Ali Akbar

Abstract excerpt

INTRODUCTION: Irritable bowel syndrome (IBS) is a multifactorial functional gastrointestinal disorder, characterized by recurrent abdominal pain and altered bowel habits. Proinflammatory cytokines can play an important role in intestinal inflammation, while their production is under genetic control. METHODS: This study was performed in a group of patients with IBS to analyze the genotype frequencies of a number...

Topics

Adult
DNA Mutational Analysis
Female
Gene Frequency
Genetic Association Studies
Genetic Predisposition to Disease
Genotype
Haplotypes
Humans
Interleukin-1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Interleukin-6

Iran

Irritable Bowel Syndrome

Male

Middle Aged

Polymorphism, Genetic

Tumor Necrosis Factor-alpha

Source

Open in PubMed

Identifiers

PMID: 19844779
DOI: 10.1007/s10875-009-9342-4

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