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Article

Trophoblast stem cells differentiate in vitro into invasive trophoblast giant cells.

Developmental biology - 15 Jul 2004

Hemberger Myriam, Hughes Martha, Cross James C

Abstract excerpt

Trophoblast cells are characterized by an invasive behavior into the surrounding uterine tissue. In rodents, an early peri-/endovascular type of invasion exerted by trophoblast giant cells can be distinguished from a late interstitial type carried out by glycogen trophoblast cells. Analysis of the molecular mechanisms of trophoblast invasion has been hampered, however, by the complex temporal and spatial patterns...

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PMID: 15223340
DOI: 10.1016/j.ydbio.2004.03.040

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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