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Phosphatidylinositol 3 kinase modulation of trophoblast cell differentiation

14 Sept 2010

Abstract excerpt

BACKGROUND: The trophoblast lineage arises as the first differentiation event during embryogenesis. Trophoblast giant cells are one of several end-stage products of trophoblast cell differentiation in rodents. These cells are located at the maternal-fetal interface and are capable of invasive and endocrine functions, which are necessary for successful pregnancy. Rcho-1 trophoblast stem cells can be effectively...

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PMID: 20840781
DOI: 10.1186/1471-213x-10-97

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