Article

Spatially resolved single-cell multiomics map of human trophoblast differentiation in early pregnancy

2022-11-06

Abstract excerpt

The relationship between the human placenta, the extraembryonic organ built by the fetus, and the decidua, the mucosal layer of the uterus, is essential to nurture and protect the fetus during pregnancy. Extravillous trophoblast cells (EVTs) anchor the placenta and infiltrate the decidua, transforming the maternal arteries into high conductance vessels. Defects in trophoblast invasion and arterial transformation e...

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Literature Corpus work: 43f9d0d0-93e3-53a5-856d-07dd2b6468e1
DOI: 10.1101/2022.11.06.515326

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