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Article

Development and function of trophoblast giant cells in the rodent placenta

29 Oct 2009

Abstract excerpt

Trophoblast giant cells (TGCs) are the first cell type to terminally differentiate during embryogenesis and are of vital importance for implantation and modulation of post-implantation placentation. TGCs are mononuclear and polyploid but are heterogenous and dynamic. At least four different subtypes of TGCs are present within the mature placenta that have distinct cell lineage origins. The development of TGCs is...

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PMID: 19876834
DOI: 10.1387/ijdb.082768dh

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