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Investigation of human trophoblast invasion in vitro

26 Mar 2020

Abstract excerpt

BACKGROUND: In humans, inadequate trophoblast invasion into the decidua is associated with the 'great obstetrical syndromes' which include pre-eclampsia, foetal growth restriction (FGR) and stillbirth. The mechanisms regulating invasion remain poorly understood, although interactions with the uterine environment are clearly of central importance. Extravillous trophoblast (EVT) cells invade the uterus and...

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PMID: 32441309
DOI: 10.1093/humupd/dmaa017

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