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Article

Preliminary observations on APOE epsilon4 allele and progression of disability in multiple sclerosis.

Archives of neurology - 1 Dec 1999

Chapman J, Sylantiev C, Nisipeanu P, Korczyn A D

Abstract excerpt

BACKGROUND: Apolipoprotein E expression is increased in regenerating neural tissue and the APOE epsilon4 allele is associated with impaired neuronal repair. Since repair is essential for the restoration of central nervous system function following multiple sclerosis (MS) relapses, APOE genotype may influence clinical progression of the disease. OBJECTIVE: To examine the association of the APOE genotype with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 10593303
DOI: 10.1001/archneur.56.12.1484

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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Preliminary observations on APOE epsilon4 allele and progression of disability in multiple sclerosis.PMID 10593303Read ↗

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