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Article

Influence of apolipoprotein E epsilon4 genotype on brain tissue integrity in relapsing-remitting multiple sclerosis.

Archives of neurology - 1 Apr 2004

De Stefano Nicola, Bartolozzi Maria Letizia, Nacmias Benedetta, Zipoli Valentina, Mortilla Marzia, Guidi Leonello, Siracusa Gianfranco, Sorbi Sandro, Federico Antonio, Amato Maria Pia

Abstract excerpt

BACKGROUND: Recent clinical and imaging studies have raised the hypothesis that patients with multiple sclerosis (MS) and the apolipoprotein E (ApoE) epsilon4 allele may have a more severe disease course than those without the ApoE epsilon4 allele. This seems to be related to more extensive tissu...

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Share to Apolipoprotein E4
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15096402
DOI: 10.1001/archneur.61.4.536

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15096402-2026-09-02.1. Manifest publication-graph-cohort-2026-09-02.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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