Article
Functional protein microarrays for parallel characterisation of p53 mutants.
Proteomics - 1 Jul 2004
Boutell Jonathan M, Hart Darren J, Godber Benjamin L J, Kozlowski Roland Z, Blackburn Jonathan M
Abstract excerpt
Understanding the way in which single nucleotide polymorphisms and mutations in the human genome result in individual susceptibility to disease is a major goal in the postgenomic era. Such knowledge should accelerate the development of personalised medicine in which drug treatment can specifically match an individual's genotype. High-throughput DNA sequencing is generating the initial information required, but...
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