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Article

Single-nucleotide polymorphisms in the p53 signaling pathway.

Cold Spring Harbor perspectives in biology - 1 May 2010

Grochola Lukasz F, Zeron-Medina Jorge, Mériaux Sophie, Bond Gareth L

Abstract excerpt

The p53 tumor suppressor pathway is central both in reducing cancer frequency in vertebrates and in mediating the response of commonly used cancer therapies. This article aims to summarize and discuss a large body of evidence suggesting that the p53 pathway harbors functional inherited single-nuc...

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Identifiers

PMID: 20452958
DOI: 10.1101/cshperspect.a001032
PMCID: PMC2857176

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20452958-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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