Haplotype diversity and SNP frequency dependence in the description of genetic variation.

Abstract excerpt

Haplotype diversity is controlled by a variety of processes, including mutation, recombination, marker ascertainment and demography. Understanding the extent to which genetic variation at physically linked loci is co-inherited is crucial for the design of the HapMap project and the correct interpretation of the resulting data. In the absence of an analytical theory extensive coalescent simulations are used to...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Computer Simulation
• Share to Gene Frequency
• Share to Genetic Variation