Article
Association between the estrogen receptor beta gene and age of onset of Parkinson's disease.
Psychoneuroendocrinology - 1 Sept 2004
Westberg L, Håkansson A, Melke J, Shahabi H Niazi, Nilsson S, Buervenich S, Carmine A, Ahlberg J, Grundell M B, Schulhof B, Klingborg K, Holmberg B, Sydow O, Olson L, Johnels E B, Eriksson E, Nissbrandt H
Abstract excerpt
The purpose of this study was to investigate the potential contribution of genetic variants in the estrogen receptor beta gene to the aetiology of Parkinson's disease (PD). Several lines of evidence from human and animal studies suggest a protective role for estrogen in PD. Recently the estrogen receptor beta subtype was reported to be an important mediator of estrogen actions in the nigrostriatal dopamine...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
