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Article

Variants in estrogen-related genes and risk of Parkinson's disease.

Movement disorders : official journal of the Movement Disorder Society - 1 Jun 2011

Chung Sun Ju, Armasu Sebastian M, Biernacka Joanna M, Lesnick Timothy G, Rider David N, Cunningham Julie M, Maraganore Demetrius M

Abstract excerpt

Incidence rates of Parkinson's disease are higher in men than in women at all ages, and these differences may be a result of the neuroprotective effects of estrogen on the nigrostriatal pathway. We investigated the association of common variants in 4 estrogen-related genes with Parkinson's disease. Tagging single-nucleotide polymorphisms in the CYP19A1, ESR1, ESR2, and PRDM2 genes were selected from the...

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Source

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Identifiers

PMID: 21469201
DOI: 10.1002/mds.23604
PMCID: PMC4723424

Genes

PRDM2
ESR1
ESR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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