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Article

Positive association between an estrogen receptor gene polymorphism and Parkinson's disease with dementia

1 Jul 1999

Abstract excerpt

Parkinson's disease (PD) is a common cause of dementia in the elderly. Dementia in Alzheimer's disease (AD) and PD share common biologic and clinical features. The estrogen receptor (ER) gene is one of the susceptibility genes for AD. In order to test the hypothesis that the overlap between AD and PD may have a genetic basis, we determined ER gene polymorphisms in 13 PD patients with dementia (PDD) (age +/- SD;...

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PMID: 10362895
DOI: 10.1046/j.1468-1331.1999.640431.x

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