Article
Invasion of Africa by a single pfcrt allele of South East Asian type.
Malaria journal - 26 Apr 2006
Ariey Frédéric, Fandeur Thierry, Durand Remy, Randrianarivelojosia Milijaona, Jambou Ronan, Legrand Eric, Ekala Marie Thérèse, Bouchier Christiane, Cojean Sandrine, Duchemin Jean Bernard, Robert Vincent, Le Bras Jacques, Mercereau-Puijalon Odile
Abstract excerpt
BACKGROUND: Because of its dramatic public health impact, Plasmodium falciparum resistance to chloroquine (CQ) has been documented early on. Chloroquine-resistance (CQR) emerged in the late 1950's independently in South East Asia and South America and progressively spread over all malaria areas. CQR was reported in East Africa in the 1970's, and has since invaded the African continent. Many questions remain about...
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