Article
Real-time PCR for dihydrofolate reductase gene single-nucleotide polymorphisms in Plasmodium vivax isolates.
Antimicrobial agents and chemotherapy - 1 Jul 2004
Brega Sara, de Monbrison Frédérique, Severini Carlo, Udomsangpetch Rachanee, Sutanto Inge, Ruckert Paul, Peyron François, Picot Stéphane
Abstract excerpt
Mutations in the dhfr gene of Plasmodium vivax (pvdhfr) are associated with resistance to the antifolate antimalarial drugs. Polymorphisms in the pvdhfr gene were assessed by hybridization probe technology on the LightCycler instrument with 134 P. vivax-infected blood samples from Turkey (n = 24)...
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