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Article

Genetic variations of the dihydrofolate reductase gene of Plasmodium vivax in Mandalay Division, Myanmar.

Parasitology research - 1 Jul 2005

Na Byoung-Kuk, Lee Hyeong-Woo, Moon Sung-Ung, In Tae-Suk, Lin Khin, Maung Maung, Chung Gyung-Tae, Lee Jong-Koo, Kim Tong-Soo, Kong Yoon

Abstract excerpt

Dihydrofolate reductase (DHFR; EC1.5.1.3) is a known target enzyme for antifolate agents, which are used as alternative chemotherapeutics for chloroquine-resistant malaria. Mutations in the dhfr gene of Plasmodium vivax are thought to be associated with resistance to the antifolate drugs. In this study, we have analyzed genetic variations in the dhfr genes of clinical isolates of P. vivax (n=21) in Myanmar, to...

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PMID: 15924223
DOI: 10.1007/s00436-005-1364-0

Genes

DHFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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