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Article

Association of genetic mutations in Plasmodium vivax dhfr with resistance to sulfadoxine-pyrimethamine: geographical and clinical correlates.

Antimicrobial agents and chemotherapy - 1 Nov 2001

Imwong M, Pukrittakayamee S, Looareesuwan S, Pasvol G, Poirreiz J, White N J, Snounou G

Abstract excerpt

Mutations in the Plasmodium falciparum gene (dhfr) encoding dihydrofolate reductase are associated with resistance to antifols. Plasmodium vivax, the more prevalent malaria parasite in Asia and the Americas, is considered antifol resistant. Functional polymorphisms in the dhfr gene of P. vivax (p...

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Identifiers

PMID: 11600366
DOI: 10.1128/AAC.45.11.3122-3127.2001
PMCID: PMC90792

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-11600366-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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