Article
Molecular characterization of antifolates resistance-associated genes, (dhfr and dhps) in Plasmodium vivax isolates from the Middle East.
Malaria journal - 28 Jan 2009
Zakeri Sedigheh, Motmaen Shadi Rabiei, Afsharpad Mandana, Djadid Navid Dinparast
Abstract excerpt
BACKGROUND: In Iran, co-infections of Plasmodium vivax and Plasmodium falciparum are common and P. vivax infections are often exposed to sulphadoxine-pyrimethamine (SP). In the present study, the frequency distribution of mutations associated to SP resistance was investigated in pvdhfr and pvdhps genes from field isolates. METHODS: Clinical isolates of P. vivax were collected in two different malaria endemic...
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