Article
Unexpected complexity in the haplotypes of commonly used inbred strains of laboratory mice.
Proceedings of the National Academy of Sciences of the United States of America - 29 Jun 2004
Yalcin B, Fullerton J, Miller S, Keays D A, Brady S, Bhomra A, Jefferson A, Volpi E, Copley R R, Flint J, Mott R
Abstract excerpt
Investigation of sequence variation in common inbred mouse strains has revealed a segmented pattern in which regions of high and low variant density are intermixed. Furthermore, it has been suggested that allelic strain distribution patterns also occur in well defined blocks and consequently could be used to map quantitative trait loci (QTL) in comparisons between inbred strains. We report a detailed analysis of...
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