Article
Whole-Genome Sequencing of Inbred Mouse Strains Selected for High and Low Open-Field Activity.
Behavior genetics - 1 Jan 2021
Thomas Aimee L, Evans Luke M, Nelsen Michaela D, Chesler Elissa J, Powers Matthew S, Booher Winona C, Lowry Christopher A, DeFries John C, Ehringer Marissa A
Abstract excerpt
We conducted whole-genome sequencing of four inbred mouse strains initially selected for high (H1, H2) or low (L1, L2) open-field activity (OFA), and then examined strain distribution patterns for all DNA variants that differed between their BALB/cJ and C57BL/6J parental strains. Next, we assessed genome-wide sharing (3,678,826 variants) both between and within the High and Low Activity strains. Results suggested...
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