Article
Haplotype-based genetics in mice and rats.
Trends in genetics : TIG - 1 Jun 2005
Cuppen Edwin
Abstract excerpt
Haplotype blocks are conceptually defined as genomic segments harbouring sets of coupled polymorphisms that reflect a common ancestral origin. Experimentally, however, haplotype blocks are characterized using computational algorithms based on incomplete inventories of polymorphisms. Haplotype blocks and their deduced strain-distribution patterns are considered to be extremely powerful for use in genetic...
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