Article
Mutations affecting gonadal development in Medaka, Oryzias latipes.
Mechanisms of development - 1 Jul 2004
Morinaga Chikako, Tomonaga Takeshi, Sasado Takao, Suwa Hiroshi, Niwa Katsutoshi, Yasuoka Akihito, Henrich Thorsten, Watanabe Tomomi, Deguchi Tomonori, Yoda Hiroki, Hirose Yukihiro, Iwanami Norimasa, Kunimatsu Sanae, Okamoto Yasuko, Yamanaka Toshiyuki, Shinomiya Ai, Tanaka Minoru, Kondoh Hisato, Furutani-Seiki Makoto
Abstract excerpt
A gonad is formed from germ cells and somatic mesodermal cells through their interactions. Its development is coupled with the determination and differentiation of the sex and sex-associated traits. We carried out a large-scale screening of Medaka mutants in which gonadal development is affected. Screening was performed on larvae at 8 days posthatching for abnormal abundance and/or distribution of germ cells...
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