Article
Mutations affecting early distribution of primordial germ cells in Medaka (Oryzias latipes) embryo.
Mechanisms of development - 1 Jul 2004
Sasado Takao, Morinaga Chikako, Niwa Katsutoshi, Shinomiya Ai, Yasuoka Akihito, Suwa Hiroshi, Hirose Yukihiro, Yoda Hiroki, Henrich Thorsten, Deguchi Tomonori, Iwanami Norimasa, Watanabe Tomomi, Kunimatsu Sanae, Osakada Masakazu, Okamoto Yasuko, Kota Yasuko, Yamanaka Toshiyuki, Tanaka Minoru, Kondoh Hisato, Furutani-Seiki Makoto
Abstract excerpt
The development of germ cells has been intensively studied in Medaka (Oryzias latipes). We have undertaken a large-scale screen to identify mutations affecting the development of primordial germ cells (PGCs) in Medaka. Embryos derived from mutagenized founder fish were screened for an abnormal distribution or number of PGCs at embryonic stage 27 by RNA in situ hybridization for the Medaka vasa homologue (olvas)....
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