Article
A genetic screen for mutations affecting gonad formation in Drosophila reveals a role for the slit/robo pathway.
Developmental biology - 15 May 2011
Weyers Jill J, Milutinovich Allison B, Takeda Yasuko, Jemc Jennifer C, Van Doren Mark
Abstract excerpt
Organogenesis is a complex process requiring multiple cell types to associate with one another through correct cell contacts and in the correct location to achieve proper organ morphology and function. To better understand the mechanisms underlying gonad formation, we performed a mutagenesis screen in Drosophila and identified twenty-four genes required for gonadogenesis. These genes affect all different aspects...
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